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. 2020 Jun 12;13:91. doi: 10.1186/s13041-020-00631-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Regulation of BDNF expression by chronic unpredictable stress. Total Bdnf mRNA levels in the mPFC (a) and the hippocampus (b) of control and CUS groups. c Immunoblots showing BDNF protein levels in the mPFC of control and CUS groups. d Correlation analysis between SPT, NSFT, or FST and total Bdnf mRNA levels in the mPFC. e Correlation analysis between, SPT, NSFT, or FST and BDNF protein levels in mPFC of CUS mice. f Correlation analysis between SPT, NSFT, or FST and total Bdnf mRNA levels in the hippocampus of CUS mice. ***p < 0.001 compared with control group