Table 5.
GI symptoms and QOL comparisons between IBS-D patients with and without SIBO eradication after rifaximin treatment
| Clinical factors | LHBT (+) | LHBT (−) | P value |
|---|---|---|---|
| GI symptoms (mean) | 7.88 ± 6.15 | 8.95 ± 5.23 | 0.531 |
| Abdominal discomfort | 1.64 ± 1.29 | 1.20 ± 1.20 | 0.243 |
| Abdominal distension | 0.92 ± 1.04 | 0.90 ± 1.29 | 0.956 |
| Abdominal pain | 1.64 ± 1.35 | 1.45 ± 1.28 | 0.631 |
| Defecatory urgency | 1.32 ± 1.44 | 2.05 ± 1.28 | 0.078 |
| Diarrhea | 1.20 ± 1.29 | 1.95 ± 1.10 | 0.051 |
| Incomplete evacuation | 1.16 ± 1.11 | 1.55 ± 1.15 | 0.256 |
| Quality of life (mean) | 579.93 ± 106.11 | 599.05 ± 88.29 | 0.513 |
| Physical Functioning | 96.20 ± 4.63 | 98.25 ± 3.73 | 0.107 |
| Role-physical | 70.00 ± 35.36 | 81.25 ± 25.49 | 0.222 |
| Bodily pain | 71.92 ± 14.29 | 73.68 ± 15.41 | 0.697 |
| General Health | 53.60 ± 19.72 | 53.85 ± 16.69 | 0.963 |
| Vitality | 63.80 ± 14.74 | 64.00 ± 15.01 | 0.965 |
| Social Functioning | 84.57 ± 12.92 | 82.95 ± 13.41 | 0.685 |
| Role-Emotional | 72.00 ± 32.89 | 81.67 ± 33.29 | 0.336 |
| Mental Health | 67.84 ± 17.42 | 63.40 ± 18.55 | 0.417 |
Note: IBS, irritable bowel syndrome; IBS-D, diarrhea-predominant IBS; GI symptoms, gastrointestinal symptoms; QOL, quality of life; SIBO, small intestinal bacterial overgrowth