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. 2020 Jun 11;11:232. doi: 10.1186/s13287-020-01755-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Schematic diagram of the distribution and main markers of epidermal SCs. iSCs are clustered and interspersed in the basal layer of epidermis. Most of the hair follicular SCs reside in the bulge. The isthmus SCs localize in the junction between the hair follicle and sebaceous glands. The upper part of the isthmus contains infundibular SCs. Sebaceous gland duct SCs are located at the opening of the glands while sebaceous gland SCs are located in the glands. Each population of epidermal SCs expresses distinct markers, which are shown in the colored boxes