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. 2020 Jun 11;21:145. doi: 10.1186/s12931-020-01410-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Serum levels of esRAGE in patients with IPF and control subjects

The serum levels of endogenous secretory receptor for advanced glycation end products (esRAGE) in patients with idiopathic pulmonary fibrosis (IPF) were significantly lower than those in controls (162.0 ± 102.4 ng/ml and 200.7 ± 107.3 ng/ml, p = 0.009, respectively). Key: boxes represent the 25th to 75th percentiles; solid lines within the boxes show the median values; whiskers are the 10th and 90th percentiles; and the small circles represent outliers ^*p < 0.05 (Mann-Whitney U-test) SD, standard deviation