Table 1.
TP53-mutated AML | TP53-wild type AML | ||||||||
---|---|---|---|---|---|---|---|---|---|
AML-12 | AML-83 | AML-135 | AML-147 | AML-172 | AML-253 | AML-277 | AML-71 | AML-132 | |
IC50 (MTT, nM) | 3.021 ± 1.145 | 0.656 ± 0.061 | 2.017 ± 0.205 | 1.252 ± 0.325 | 2.405 ± 0.344 | 1.274 ± 0.148 | 2.075 ± 0.213 | 3.438 ± 1.295 | 3.276 ± 0.979 |
IC50 (CFU, nM) | 0.152 ± 0.021 | 0.113 ± 0.067 | 0.232 ± 0.061 | 0.237 ± 0.014 | 0.376 ± 0.121 | 0.326 ± 0.078 | 0.833 ± 0.039 | 0.184 ± 0.179 | 0.175 ± 0.098 |