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. 2019 Feb 27;39(2):100–118. doi: 10.1002/npr2.12052

Figure 3.

Figure 3

Normal sociability and reduced social novelty preference in aged C57BL/6J mice. (A‐E) Social interaction test: (A) distance traveled (cm), (B) number of contacts, (C) total duration of contacts (s), (D) total duration of active contacts (s), and (E) mean duration of contact (s). (F‐I) Three‐chamber social approach test: (F) time spent in the chamber with an empty cage, the center chamber, and the chamber with a cage containing a stranger mouse (stranger 1). (G) Time spent around the empty cage and the cage with stranger 1. (H) Time spent in the chamber with the cage containing stranger 1, the center chamber, and the chamber with a cage containing a novel unfamiliar mouse (stranger 2). (I) Time spent around the cage containing stranger 1 and the cage containing stranger 2. Values are means ± SEM. Asterisks indicate significant differences between groups after Bonferroni correction for multiple comparisons (P < 0.0083). Daggers represent statistical significance with paired t test (P < 0.05)