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. 2020 Jun 12;128(6):067010. doi: 10.1289/EHP6508

Figure 2.

Figure 2 is a heatmap of a cluster diagram, plotting concentration (microgram per milliliter), ranging from 0 to 6.2 in increments of 3.1, 6.2 to 13 in increments of 6.8, 13 to 25 in increments of 12, 25 to 50 in increments of 25, 50 to 100 in increments of 50, and 100 to 200 in increments of 100 (y-axis) across Sm subscript 2 O subscript 3, Eu subscript 2 O subscript 3, La subscript 2 O subscript 3, Yb subscript 2 O subscript 3, Gd subscript 2 O subscript 3, Dy subscript 2 O subscript 3, Y subscript 2 O subscript 3, Nd subscript 2 O subscript 3, Er subscript 2 O subscript 3, Mn subscript 2 O subscript 3, MnO subscript 2, Fe subscript 3 O subscript 4, In subscript 2 O subscript 3, Al subscript 2 O subscript 3, Fe subscript 2 O subscript 3, ZrO subscript 2, HfO subscript 2, TiO subscript 2, Sb subscript 2 O subscript 3, CuO, Ni subscript 2 O subscript 3, WO subscript 3, Cr subscript 2 O subscript 3, NiO, Bj subscript 2 O subscript 3, Co subscript 3 O subscript 4, SnO subscript 2, CeO subscript 2, CoO, and ZnO (x-axis) for fold changes of IL-1 beta production, namely, 0, 1, 2, 5, 10, 20, 30, and 50.

Fold changes of IL-1β production (FCIL-1β) in metal oxide nanomaterials (MeONPs)-treated THP-1 cells. THP-1 cells were exposed to 0, 3.1, 6.2, 13, 25, 50, 100, and 200μg/mL MeONPs for 24 h. IL-1β levels in supernatants were quantified by ELISA. FCIL-1β was calculated by Equation 3. The FCIL-1β was expressed as the mean of three replicates and added in the heatmap.