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The dimeric Tn5 transpososome. The domain colors correspond to those shown in Fig. 2, where the NTD is in blue, the catalytic core is in orange, and the C-terminal dimerization domain is in purple. The four-stranded insertion into the RNaseH-like catalytic domain is shown in red. The residues comprising the DDE motif (D97, D188, and E326) are shown in ball-and-stick representation. PDB code used to generate figure: 1MUH.
