Table.
Endpoints used in clinical studies planned or done during the COVID-19 outbreak
| Registered studies (n=1135)* | Specific metrics | |
|---|---|---|
| Viral burden | 148 | Quantitative PCR |
| Mortality | 118 | .. |
| Duration of hospital or intensive care unit stay | 32 | .. |
| Symptoms | 45 | Fever, vital signs, cough |
| Progression and resolution | 175 | Multiple measure, scales |
| Lung injury and function | 101 | Oxygen saturation, Murray score, oxygenation index |
| Other clinical measures | 117 | .. |
| Imaging findings | 76 | CT scan, chest x-ray, echocardiogram |
| Biomarkers | 73 | C-reactive protein, cardiac enzymes, cytokines |
| Depression, anxiety, long-term quality of life | 63 | .. |
| Co-infection, acute kidney injury, myocardial injury | 15 | .. |
*
Not all studies listed their specific outcomes, or were studies whose outcomes did not reflect patient outcomes