Table 1:
Inhibitorsa | Substrates | Concordance, n (%) (n= 89 pairs) |
---|---|---|
All | All | 55 of 89 (62) |
Moderate | Sensitive | 10 of 18 (56) |
Moderate | Moderate sensitive | 4 of 9 (44) |
Weak | Sensitive | 17 of 30 (57) |
Weak | Moderate sensitive | 24 of 32 (75) |
Cimetidine was classified only as a weak inhibitor per the FDA Table of Inhibitors when determining concordance.
Concordance was defined as the inhibitor’s observed classification matched the classification per the FDA Table of Inhibitors.