Skip to main content
. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Clin Pharmacol Ther. 2020 Feb 13;108(1):116–125. doi: 10.1002/cpt.1768

Table 1:

Concordance by Classification per FDA Table of Inhibitors

Inhibitorsa Substrates Concordance, n (%)
(n= 89 pairs)
All All 55 of 89 (62)
 Moderate  Sensitive 10 of 18 (56)
 Moderate  Moderate sensitive 4 of 9 (44)
 Weak  Sensitive 17 of 30 (57)
 Weak  Moderate sensitive 24 of 32 (75)
a,

Cimetidine was classified only as a weak inhibitor per the FDA Table of Inhibitors when determining concordance.

Concordance was defined as the inhibitor’s observed classification matched the classification per the FDA Table of Inhibitors.