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Recommendations for FDA Table of Inhibitors
| Moderate Inhibitor | Weak Inhibitor | Removal from table |
|---|---|---|
| cimetidine, cinacalcet, duloxetine, fluvoxamine, mirabegrona | abiraterone, amiodarone, celecoxibb, cimetidine, clobazam, cobicistat, desvenlafaxine, escitalopram, fluvoxamine, labetalol, lorcaserin, ritonavir, sertraline, vemurafenib | Desvenlafaxine |
Genotype should be considered, appears to moderately inhibit only when individuals are NMs
Only at doses > 200 mg total daily dose
