Table 4.

Differences in radiomic values between control and sarcoidosis subjects by lobe. Negative values indicate lower average radiomic values in the healthy controls as compared to the sarcoidosis population. Results are presented as mean (95% CI). P-values indicate whether the group effect changed significantly across lobes, with significant results bolded.

Outcome	Left Upper Lobe	Left Lower Lobe	Right Upper Lobe	Right Middle Lobe	Right Lower Lobe	P-value
Mean	−11.39 (−19.66, −3.12)	−11.08 (−19.35, −2.81)	−12.53 (−20.80, −4.26)	−7.10 (−15.37, 1.18)	−10.55 (−18.82, −2.28)	0.3943
SD	−15.58 (−20.08, −11.09)	−9.14 (−13.64, −4.65)	−17.03 (−21.52, −12.53)	−13.45 (−17.95, −8.96)	−11.38 (−15.87, −6.88)	<0.0001
Skew	0.63 (0.46, 0.79)	0.42 (0.26, 0.59)	0.64 (0.48, 0.81)	0.60 (0.44, 0.77)	0.49 (0.32, 0.65)	0.0002
Kurtosis	6.67 (5.19, 8.15)	3.90 (2.41, 5.38)	6.62 (5.14, 8.11)	6.64 (5.15, 8.12)	4.95 (3.46, 6.43)	<0.0001
Contrast	1.06 (0.30, 1.83)	0.69 (−0.07, 1.46)	0.91 (0.15, 1.68)	1.41 (0.64, 2.18)	0.79 (0.03, 1.56)	0.0105
Autocorrelation	−0.87 (−1.26, −0.48)	−0.61 (−1.00, −0.22)	−0.74 (−1.13, −0.35)	−0.97 (−1.36, −0.58)	−0.62 (−1.01, −0.23)	0.0086
Energy (x1000)	−0.44 (−0.67, −0.20)	−0.25 (−0.49, −0.01)	−0.39 (−0.62, −0.15)	−0.43 (−0.66, −0.19)	−0.32 (−0.55, −0.08)	0.0873
Homogeneity (x100)	−1.01 (−1.76, −0.26)	−0.60 (−1.35, 0.15)	−0.83 (−1.58, −0.08)	−1.22 (−1.97, −0.47)	−0.72 (−1.47, 0.03)	0.0559