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. 2020 Jun 12;8(11):e14436. doi: 10.14814/phy2.14436

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© 2020 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Elastic Matrix Production shown as the results of Fastin assay for total elastin (a), results of Hoechst Dye Assay for DNA Content, representing cell proliferation (b), and elastin content per cell (c) for wildtype (WT), nulliparous (N), multiparous nonprolapsed (MNP) and multiparous prolapsed (MP) mice. Bars represent mean +/− standard error of the mean of 3–6 samples/group. Repeated measures mixed regression methods with pairwise comparisons corrected using a Bonferroni correction. The following symbols denote a significant difference (p < .05) compared to the group in parentheses: ^# (wildtype; WT) and +(nulliparous; N)