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. 2020 Jun 12;3(6):e207247. doi: 10.1001/jamanetworkopen.2020.7247

Table 2. Outcomes for Individual Cardiovascular Risk Factors According to Study Group.

Outcome Intervention group Control group Between-group difference, mean (95% CI)a
Mean (SD) Change, mean (95% CI)a Mean (SD) Change, mean (95% CI)a
Baseline 18 mo Baseline 18 mo
Continuous outcomes
Blood pressure, mm Hg
Systolicb 118.1 (13.0) 116.5 (12.9) −3.9 (−1.5 to 0.8) 120.1 (14.5) 120.2 (16.2) 0.2 (−2.1 to 2.5) −1.8 (−5.1 to 1.5)
Diastolic 75.3 (8.2) 73.9 (9.2) −3.0 (−1.5 to 0.1) 74.9 (9.3) 74.7 (11.1) 0.2 (−1.3 to 1.7) −1.7 (−3.8 to 0.5)
Total cholesterol, mg/dLb 178.9 (42.1) 171.8 (38.3) −7.7 (−14.2 to −1.3) 181.1 (41.6) 177.7 (48.7) −3.4 (−9.7 to 2.9) −4.3 (−13.3 to 4.7)
Low-density lipoprotein, mg/dL 101.9 (36.8) 93.7 (33.5) −8.5 (−13.9 to −3.3) 101.0 (33.4) 97.3 (35.9) −3.2 (−8.4 to 1.9) −5.4 (−12.7 to 2.0)
High-density lipoprotein, mg/dLb 49.2 (15.3) 50.7 (14.8) 1.5 (−0.5 to 3.5) 50.2 (19.3) 51.0 (17.7) 0.5 (−1.4 to 2.4) 1.0 (−1.8 to 3.8)
Trigylcerides, mg/dL 140.2 (74.3) 141.0 (76.9) 0.6 (−14.8 to 16.0) 156.6 (106.7) 149.0 (111.1) −7.5 (−22.5 to 7.6) 8.1 (−13.4 to 29.6)
Fasting glucose, mg/dL 106.5 (36.7) 106.7 (45.2) 0.5 (−6.7 to 7.6) 110.6 (36.9) 117.4 (60.0) 8.1 (1.1 to 15.0) −7.6 (−17.6 to 2.4)
Glycated hemoglobin A1C, % 6.0 (1.2) 5.9 (1.3) −0.1 (−0.3 to 0.1) 6.3 (1.4) 6.2 (1.8) −0.0 (−0.2 to 0.1) −0.0 (−0.3 to 0.2)
Body mass indexc 34.4 (7.8) 33.7 (7.7) −0.8 (−1.3 to −0.2) 32.9 (6.6) 32.1 (6.6) −0.9 (−1.4 to −0.4) 0.1 (−0.7 to 0.9)
Binary outcomes
Medication for hypertension, No. (%)b 63 (47.7) 70 (53.0) 7.99 (1.16 to 14.81)d 65 (47.5) 66 (48.2) −1.87 (−5.04 to 8.80)d 6.11 (−3.61 to 15.84)e
Diabetes, No. (%)b 42 (31.8) 46 (34.9) 4.74 (1.11 to 8.36)d 51 (37.2) 60 (43.8) 8.51 (3.89 to 13.14)d −3.78 (−9.65 to 2.10)e
Tobacco smoking, No. (%)b 65 (49.2) 47 (35.6) −11.81 (−18.32 to −5.31)d 73 (53.3) 67 (48.9) −1.32 (−5.78 to 3.14)d −10.50 (−18.39 to −2.59)e

SI conversion factors: to convert cholesterol to millimoles per liter, multiply by 0.0259; glycated hemoglobin A1C to proportion of total hemoglobin, multiply by 0.01; triglycerides to millimoles per liter, multiply by 0.0113; and glucose to millimoles per liter, multiply by 0.0555.

a

Mixed-effects repeated measures model-based estimates.

b

Components of the Global Framingham Risk Score.

c

Body mass index is calculated as weight in kilograms divided by height in meters squared.

d

Data are absolute change in prevalence, mean (95% CI), calculated with generalized estimating equations–based population-average estimates.

e

Data are net change in prevalence, mean (95% CI), calculated with generalized estimating equations–based population-average estimates.