Figure 5.

GCN5 is a master regulator of responses to environmental stimuli. GCN5 promotes the deposition of H3K14ac on the 5′ end of its target genes involved in heat stress response, response to light or inhibition of SA accumulation and functions as a positive regulator of these genes. By contrast it antagonizes H3K14 acetylation of genes involved in biotic stress response and thereby represses their expression. In this way, GCN5 may function to keep a balance between biotic and abiotic stress responses.