Table 2.
Performance (ARI and AMI) of different clustering methods from ten times analyses of the in-house human PBMC real dataset
| ARI | AMI | |
|---|---|---|
| Mean (SD), [range] | Mean (SD), [range] | |
| Single source clustering - RNA only | ||
| K-means | 0.547 (0.073), [0.429, 0.681] | 0.613 (0.062), [0.474, 0.707] |
| TSCAN | 0.476 (N/A), [N/A] | 0.574 (N/A), [N/A] |
| SC3 | 0.561 (0.017), [0.540, 0.589] | 0.606 (0.022), [0.560, 0.644] |
| DIMM-SC | 0.563 (0.101), [0.366, 0.682] | 0.598 (0.069), [0.488, 0.707] |
| Seurat | 0.675 (N/A), [N/A] | 0.732 (N/A), [N/A] |
| Single source clustering - protein only (complete list) | ||
| K-means | 0.930 (0.120), [0.702, 0.989] | 0.931 (0.072), [0.794, 0.968] |
| TSCAN | 0.929 (N/A), [N/A] | 0.881 (N/A), [N/A] |
| SC3 | 0.921 (0.039), [0.816, 0.951] | 0.891 (0.048), [0.760, 0.930] |
| DIMM-SC | 0.988 (0.005), [0.975, 0.993] | 0.971 (0.014), [0.935, 0.983] |
| Seurat | 0.996 (N/A), [N/A] | 0.976 (N/A), [N/A] |
| Multi-source joint clustering | ||
| K-means | 0.718 (0.102), [0.562, 0.805] | 0.755 (0.057), [0.659, 0.803] |
| TSCAN | 0.563 (N/A), [N/A] | 0.619 (N/A), [N/A] |
| SC3 | 0.798 (0.108), [0.620, 0.938] | 0.788 (0.068), [0.690, 0.881] |
| MV-NMF | 0.861 (0.115), [0.710, 0.989] | 0.871 (0.086), [0.780, 0.969] |
| PC-MSC | 0.703 (0.094), [0.573, 0.950] | 0.798 (0.048), [0.705, 0.909] |
| BREM-SC | 0.966 (0.025), [0.917, 0.985] | 0.944 (0.039), [0.869, 0.970] |