Figure 3.

Examples of simple motifs built by open conformers. (A) Example of OP12 motif (red) assigned to step G110–C111 from chain B of 2pn4 (73). The step is capable of binding three sequentially distant parts of the molecule or three different chains, one in the center, one in light blue, one in light yellow. (B) OP15 with both bases nearly in one plane often pairs with OP08 in the opposite strand (OP15 in red, OP08 in blue, motif from sarcin/ricin domain of 28S rRNA, step G10–U11 from chain A of 1q96 (50). Drawn by ChimeraX (74).