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. 2020 May 14;48(11):6367–6381. doi: 10.1093/nar/gkaa383

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Examples of tetraloop and tetraloop involving motifs. (A) Tetraloop from 4lvz (75) contains OP03 (step G59-A60), followed by a series of A-like NtC classes. (B) The open conformation OP05 preceding the actual tetraloop G2738–A2739–G2740–A2741 in the step C2737–G2738 of 1vq8 (76) enables a kissing loop motif to a distant part of the molecule. (C) Two OPN (OP09 and OP20), are adjacent to a ZZ1S step in nucleotides U2144–C2145–C2146–G2147 of (77). (D) The loop from 4qvi (77) built by OP04 (step G2168–A2169) and IC01 (step A2170–A2171) pairs with distant base (A2119), a part of OP13. Drawn by ChimeraX (74).