TABLE 1.
In vivo tumor growth inhibition profile in Ba/F3 tumor xenografts in mice
| Group | Animals (N) | Tumor weight (g) | Relative tumor proliferation rate (T/C, %) | Tumor cell growth inhibition rate (%) | P a value | P b value |
|---|---|---|---|---|---|---|
| Control | 8 | 2.357 ± 0.340 | – | – | – | – |
| CER | 8 | 0.347 ± 0.083 | 15.1 | 84.9 | .000 | .104 |
| PD‐L1 | 8 | 1.426 ± 0.243 | 80.0 | 20.0 | .140 | .000 |
| CER plus PD‐L1 | 8 | 0.192 ± 0.059 | 8.2 | 91.9 | .000 | – |
Tumor cell growth inhibition rate: 1 − T/C.
–, not applicable; T/C, treatment/control.
a
Compared with control group.
b
Compared with ceritinib (CER) plus programmed cell death ligand‐1 (PD‐L1) group.