Skip to main content
. Author manuscript; available in PMC: 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22;10(4):363–378.e12. doi: 10.1016/j.cels.2020.03.004
Parameter Description
ron The rate at which DNA is activated.
roff The rate at which DNA is inactivated.
rprod Synthesis rate of mRNA.
rdeg Degradation rate of mRNA.
radd Parameter determining the contribution of the additional DNA activation rate upon gene regulation.
d Factor by which the mRNA synthesis rate is increased when in an active DNA state (in comparison to basal synthesis rate in DNA inactive state), >1.
k Dissociation constant of the Hill function.
n Hill coefficient.