. 2020 Jun 13;21:129. doi: 10.1186/s12881-020-01065-3

Table 2.

BMI levels in subgroups defined by the investigated genotypes

		Allele		BMI (kg/m²)
Gene	SNP	ref.	var.	ref. homo-zygote.	minor allele carriers	p
NADSYN1	rs7935125	C	A	25.3 ± 4.2	26.0 ± 4.5	0.31
GC	rs17467825	A	G	26.4 ± 4.6	25.6 ± 4.4	0.045
	rs222054	C	G	25.9 ± 4.5	26.1 ± 4.6	0.76
	rs4588	G	T	26.4 ± 4.6	25.6 ± 4.4	0.048
	rs7041	A	C	25.4 ± 4.1	26.2 ± 4.6	0.13
CYP2R1	rs1993116	A	G	26.5 ± 4.5	25.9 ± 4.5	0.295
	rs10500804	T	G	26.4 ± 4.6	25.8 ± 4.5	0.15
	rs11023374	T	C	26.5 ± 4.4	25.3 ± 4.4	0.006^a
CYP24A1	rs4809959	A	G	25.9 ± 4.1	26.0 ± 4.6	0.89
	rs927650	T	C	26.0 ± 4.4	25.9 ± 4.5	0.89
	rs4809960	T	C	26.1 ± 4.4	25.8 ± 4.7	0.49
	rs2209314	T	C	25.9 ± 4.4	26.2 ± 4.8	0.41
	rs6022999	A	G	26.1 ± 4.3	25.8 ± 4.8	0.54
	rs2181874	G	A	25.8 ± 4.3	26.2 ± 4.8	0.37
	rs2585428	C	T	25.9 ± 4.1	26.0 ± 4.7	0.72
	rs3787555	C	A	26.4 ± 4.4	25.5 ± 4.6	0.038
	rs2762939	G	C	25.7 ± 4.4	26.4 ± 4.6	0.11
	rs2244719	C	T	26.1 ± 4.0	25.9 ± 4.7	0.74
	rs2762941	G	A	25.7 ± 4.3	26.1 ± 4.6	0.37
VDR	rs1544410	G	A	26.1 ± 4.4	25.9 ± 4.6	0.64
	rs3890733	C	T	26.3 ± 4.8	25.8 ± 4.3	0.20
	rs2853564	G	A	24.5 ± 4.3	26.2 ± 4.5	0.007^a
	rs7302235	T	C	25.5 ± 4.2	26.6 ± 4.9	0.017^a

Univariate associations between SNPs and BMI were analyzed using two-sample t-tests

^a marks association that remained significant after FDR correction

Abbreviations: CYP24A1 vitamin D 24-hydroxylase gene (cytochrome P450 family 24 subfamily A member 1), CYP2R1 vitamin D 25-hydroxylase gene (cytochrome P450 family 2 subfamily R member 1), GC vitamin D binding protein, “group-specific component” gene, NADSYN1 glutamine-dependent NAD(+) synthetase, VDR vitamin D receptor

Bold text highlights where p < 0.05