Table 2.
Multivariate regression analysis for risk factors of lymph node metastasis among clinical stage IA (cT1N0M0) peripheral non-small cell lung cancer patients.
Characteristics | Odds Ratio | 95% Confidence Interval | P value |
---|---|---|---|
LN metastasis | |||
Age (young VS elderly) | 1.691 | 0.910–3.142 | 0.097 |
Gender (male VS female) | 0.730 | 0.423–1.259 | 0.257 |
Tumor consistency (pure solid VS part-solid/pure ground glass) | 4.505 | 1.713–11.850 | 0.002 |
Histology (adenocarcinoma VS nonadenocarcinoma) | 0.764 | 0.372–1.564 | 0.463 |
Tumor size (cm) | 1.603 | 1.007–2.551 | 0.047 |
Tumor differentiation (G3 VS G1/G2) | 3.860 | 2.243–6.643 | <0.001 |
Visceral pleural invasion (yes VS no) | 1.529 | 0.899–2.601 | 0.117 |
N1 LN metastasis | |||
Age (young VS elderly) | 2.065 | 1.049–4.064 | 0.036 |
Gender (male VS female) | 0.770 | 0.435–1.362 | 0.369 |
Tumor consistency (pure solid VS part-solid/pure ground glass) | 11.274 | 2.644–48.069 | 0.001 |
Histology (adenocarcinoma VS nonadenocarcinoma) | 0.460 | 0.226–0.938 | 0.033 |
Tumor size (cm) | 1.283 | 0.790–2.083 | 0.313 |
Tumor differentiation (G3 VS G1/G2) | 2.779 | 1.587–4.867 | <0.001 |
Visceral pleural invasion (yes VS no) | 1.615 | 0.923–2.825 | 0.093 |
N2 LN metastasis | |||
Age (young VS elderly) | 2.400 | 1.083–5.316 | 0.031 |
Gender (male VS female) | 0.612 | 0.320–1.170 | 0.137 |
Tumor consistency (pure solid VS part-solid/pure ground glass) | 3.108 | 1.033–9.349 | 0.044 |
Histology (adenocarcinoma VS nonadenocarcinoma) | 1.422 | 0.555–3.640 | 0.463 |
Tumor size (cm) | 1.516 | 0.867–2.652 | 0.145 |
Tumor differentiation (G3 VS G1/G2) | 6.250 | 3.172–12.314 | <0.001 |
Visceral pleural invasion (yes VS no) | 1.738 | 0.935–3.232 | 0.080 |
Note: LN = lymph node.