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. 2020 Jun 12;6:24. doi: 10.1038/s41523-020-0165-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Catalog of base substitutions, insertions/deletions in the 204 BBBs. Each bar represents one individual’s total number of mutations. Left panel is the case and right panel is the control. b The top 20 mutated genes in the case group (left) and control group (right). c The top mutated genes as b, adjusted by gene length. d Catalog of nonsense mutations in the 204 BBBs.