Table 3.
Comparison of long-term side effects between two study groups.
| n | NRT | RT | P | |
|---|---|---|---|---|
| n = 23 (24.8%) | n = 74 (75.2%) | |||
| Fatigue | 48 | 8 (34.8) | 40 (54.1) | 0.152 |
| Abdominal pain | 79 | 17 (73.9) | 62 (83.8) | 0.358 |
| Diarrhea | 51 | 7 (30.4) | 44 (59.5) | 0.018* |
| Constipation | 65 | 16 (69.6) | 49 (66.2) | 1.000 |
| Bloody stool | 38 | 3 (13.0) | 35 (47.3) | 0.007** |
| Dysuria | 23 | 3 (13.0) | 20 (27.0) | 0.273 |
| Urinary incontinence | 26 | 9 (39.1) | 17 (23.0) | 0.127 |
| Urinary frequency | 24 | 8 (34.8) | 16 (21.6) | 0.201 |
| Lower extremities edema | 49 | 7 (30.4) | 42 (56.8) | 0.033* |
| Vaginal discharge increasing | 21 | 8 (34.8) | 13 (17.6) | 0.090 |
| Vaginal dryness | 52 | 4 (17.4) | 48 (64.9) | 0.000** |
| Lower back pain | 32 | 4 (17.4) | 28 (37.8) | 0.117 |
| Dermal flushing | 27 | 3 (13.0) | 24 (32.4) | 0.122 |
*P < 0.05.
**P < 0.01.