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. 2020 Jun 8;13:5093–5112. doi: 10.2147/OTT.S193363

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© 2020 Pushpam et al.

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Newer targets in refractory pediatric sarcomas.

Abbreviations: BET, bromodomain extra terminal motif; CD Cyclin D, CDK 4/6 cyclin-dependent kinase 4/6; CTLA4, cytotoxic T-lymphocyte-associated protein 4; GD2, disialoganglioside 2; IGF1R, insulin-like growth factor receptor 1; LSD1, lysine-specific histone demethylase 1; MET, mesenchymal–epithelial transition; NTRK, neurotropic tropomyosin receptor kinase; PARP, poly ADP ribose polymerase; PD1, programmed death receptor 1; PDL1, programmed death receptor Ligand 1; RTK, receptor tyrosine kinase; VEGFR, vascular endothelial growth factor receptor.