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Synthesis route and 1H NMR spectrum of PLGA conjugated CDDP prodrug (CDDP-PLGA). CDDP-PLGA was synthesized by amidation of the carboxyl groups of CDDP with the amine groups of PLGA.
Abbreviations: PLGA, poly(D,L-lactic-co-glycolic); CDDP, cisplatin.
