Figure 6.

In vivo anti-tumor efficacy of CDDP-PLGA/CUR LBL NPs evaluated on NSCLC bearing mice, tumor growth (A) and body weight (B) were presented. The tumor volumes were calculated using formulation: V (mm³) = 1/2×(length)×(width)². After 21 days of injection, mice were sacrificed by cervical decapitation and the final tumor weight and body weight of mice was recorded. Data presented as mean ± SD, n = 6. * means P < 0.05.

Abbreviations: CDDP, cisplatin; CUR, curcumin; LBL, layer-by-layer; NPs, lipid-polymer hybrid nanoparticles; NSCLC, non-small cell lung cancer.