Table 1.
Participant Characteristics, by Region and Overalla
| US (N = 25) | Europeb (N = 50) | Brazil (N = 10) | Total (N = 85) | |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Sex, n (%) | ||||
| Female | 18 (72.0) | 27 (54.0) | 6 (60.0) | 51 (60.0) |
| Current age (years), mean (SD) | 48.1 (12.4) | 51.1 (12.9) | 47.3 (10.0) | 49.8 (12.5) |
| Education,cn (%) | ||||
| Primary school | 1 (4.0) | 6 (14.6) | 2 (20.0) | 9 (11.8) |
| Secondary school | 6 (24.0) | 19 (46.3) | 3 (30.0) | 28 (36.8) |
| College/university degree | 18 (72.0) | 16 (39.0) | 5 (50.0) | 39 (51.3) |
| Prefer not to answer | 0 (0) | 9 (18.0) | 0 (0) | 9 (10.6) |
| Relationship status,cn (%) | ||||
| Single | 7 (28.0) | 5 (12.2) | 2 (20.0) | 14 (18.4) |
| Cohabiting, married, or civil partnership | 13 (52.0) | 33 (80.5) | 7 (70.0) | 53 (69.7) |
| Otherd | 5 (20.0) | 3 (7.3) | 1 (10.0) | 9 (11.8) |
| Prefer not to answer | 0 (0) | 9 (18.0) | 0 (0) | 9 (10.6) |
| Race/ethnicity,cn (%) | ||||
| White | 19 (76.0) | 21 (100.0) | 10 (100.0) | 50 (89.3) |
| Black | 2 (8.0) | 0 (0) | 0 (0) | 2 (3.6) |
| Asian | 1 (4.0) | 0 (0) | 0 (0) | 1 (1.8) |
| Hispanic | 3 (12.0) | 0 (0) | 0 (0) | 3 (5.4) |
| Other | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Prefer not to answer | 0 (0) | 29 (58.0) | 0 (0) | 29 (34.1) |
| Healthcare coverage,cn (%) | ||||
| Private | 18 (72.0) | 8 (19.5) | 4 (40.0) | 30 (39.5) |
| Medicare, Medicaid, or public assistance | 7 (28.0) | 32 (78.0) | 6 (60.0) | 45 (59.2) |
| Military | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Other | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| None | 0 (0) | 1 (2.4) | 0 (0) | 1 (1.3) |
| Prefer not to answer | 0 (0) | 9 (18.0) | 0 (0) | 9 (10.6) |
| Clinical characteristics | ||||
| Age (years) at PsA diagnosis, mean (SD) | 37.6 (13.3) | 41.1 (12.9) | 37.1 (12.5) | 39.6 (13.0) |
| PsO, NRS (0–10),e mean (SD) | 4.0 (2.8) | 2.7 (3.0) | 5.4 (3.1) | 3.4 (3.0) |
| Joint/ligament pain, NRS (0–10),e mean (SD) | 4.7 (2.5) | 4.6 (2.6) | 5.6 (2.0) | 4.7 (2.5) |
| Fatigue, NRS (0–10),e mean (SD) | 5.3 (2.8) | 4.9 (2.9) | 6.5 (2.5) | 5.2 (2.8) |
| Impact, NRS (0–10),e,f mean (SD) | 5.7 (3.0) | 5.4 (3.1) | 9.1 (1.4) | 5.9 (3.1) |
| Severity of PsA, n (%) | ||||
| Mild | 9 (36.0) | 15 (30.0) | 1 (10.0) | 25 (29.4) |
| Moderate | 11 (44.0) | 23 (46.0) | 8 (80.0) | 42 (49.4) |
| Severe | 5 (20.0) | 9 (18.0) | 0 (0) | 14 (16.5) |
| Very severe | 0 (0) | 3 (6.0) | 1 (10.0) | 4 (4.7) |
| Current PsA and PsO signs and symptoms,gn (%) | ||||
| Joint pain | 22 (88.0) | 44 (88.0) | 8 (80.0) | 74 (87.1) |
| Skin patches or plaques (flaking, redness) | 20 (80.0) | 29 (58.0) | 10 (100.0) | 59 (69.4) |
| Stiffness | 17 (68.0) | 25 (50.0) | 3 (30.0) | 45 (52.9) |
| Joint swelling | 15 (60.0) | 24 (48.0) | 2 (20.0) | 41 (48.2) |
| Skin discomfort (eg itching, painful, bleeding, etc.) | 15 (60.0) | 17 (34.0) | 5 (50.0) | 37 (43.5) |
| Unusual fatigue | 9 (36.0) | 18 (36.0) | 2 (20.0) | 29 (34.1) |
| Joint damage | 5 (20.0) | 17 (34.0) | 2 (20.0) | 24 (28.2) |
| Joint tenderness | 5 (20.0) | 16 (32.0) | 2 (20.0) | 23 (27.1) |
| Swollen or inflamed (“sausage”) fingers or toes (dactylitis) | 4 (16.0) | 13 (26.0) | 2 (20.0) | 19 (22.4) |
| Inflammatory back pain (back pain/stiffness) | 6 (24.0) | 12 (24.0) | 0 (0) | 18 (21.2) |
| Sleep problems | 5 (20.0) | 10 (20.0) | 1 (10.0) | 16 (18.8) |
| Nail changes (ie pitting or small dents, separation from nail bed) | 6 (24.0) | 7 (14.0) | 1 (10.0) | 14 (16.5) |
| Tenderness or swelling of ligament/tendon that connects to the bone, commonly the heel or elbow (enthesitis) | 3 (12.0) | 6 (12.0) | 1 (10.0) | 10 (11.8) |
| Eye irritation, redness, disturbed vision | 1 (4.0) | 5 (10.0) | 0 (0) | 6 (7.1) |
Notes: aAll variables were patient-reported. bIncludes France, Germany, Italy, Spain, and the UK. cPercentages for responses other than “Prefer not to answer” do not include any patients who selected “Prefer not to answer”. dSeparated, divorced, or widowed. e0 indicated “none” and 10 indicated the “worst possible” of the variable. fBased on the question “How, if at all, have your PsA symptoms (including skin and musculoskeletal [joint, spine, swelling, tenderness] symptoms) impacted your life?”. gPatients could report >1 response; percentages total >100%.
Abbreviations: NRS, numerical rating scale; PsA, psoriatic arthritis; PsO, psoriasis; SD, standard deviation.