. 2020 Jun 13;48(4):619–626. doi: 10.1007/s15010-020-01464-x

Table 1.

Study procedures: each visit during the patient's hospital stay will register as a new visit

Visit	Enrolment
Visit	V1	V2	V3	V4	V5	V6	V7	V-discharge	V8^a	V9^a	V10^a	V11^a
Visits will be conducted three times a week until discharge from hospital^e	Monday/Wednesday/Friday starting day of enrolment							Day of discharge	6 weeks after enrolment	3 months after enrolment	6 months after enrolment	12 months after enrolment
Visit windows	–	–	–	–	–	–		–	± 1 week	± 2 week	± 3 weeks	± 3 weeks
Informed consent/authorization	×
Epidemiological data	×^d
Demographics	×^d
Medical history	×^d								×^d	×^d	×^d	×^d
Vital signs	×	×	×	×	×	×	×	×				×
Clinical symptoms	×^d	×^d	×^d	×^d	×^d	×^d	×^d	×^d	×^d	×^d	×^d	×^d
Documentation of clinical blood sample results (chemistry, haematology)^b/routine blood testing	×	×	×	×	×	×	×	×	×	×	×	×
Recording of SARS-CoV-2 PCR testing^b	×					×	×	×
SARS-CoV-2 antibody testing^c	×	×	×	×	×	×	×	×			×	×
Serum cytokines and chemokines, quantitative proteomics, circulating myeloid and lymphoid cells^c	×	×	×	×	×	×	×	×	×	×	×	×
Banked bio-materials^c	×	×	×	×	×	×	×	×	×	×	×	×
Concomitant medications	×	×	×	×	×	×	×	×	×^d	×^d	×^d	×^d
Documentation of clinical records from patient charts, e.g., parameters of mechanical ventilation, haemodynamics, etc.^b	×	×	×	×	×	×	×	×
Additional clinical data collection, e.g., chest X-ray, CT, echocardiography^b	×	×	×	×	×	×	×	×
Lung function test, echocardiography									×	×	×	×
Record of any additional hospitalizations or ER visits									×^d	×^d	×^d	×^d
Clinical severity scores (GCS, SOFA, etc.)^b	×	×	×	×	×	×	×	×
WHO Clinical Ordinal Scale	×	×	×	×	×	×	×	×	×^d	×^d	×^d	×^d
Quality of life	×^d							×^d	×^d	×^d	×^d	×^d

^aVisits may be conducted by phone

^bThese assessments are optional, only to be obtained if performed as part of standard of care

^cOnly performed if routine blood sampling is indicated

^dPatient reported data that can be collected by phone due to isolation restrictions and follow-up visits conducted by phone

^ePatients that remain in hospital beyond visit 7 will be assessed clinically. If no recovery is seen, study visits will continue until recovery or discharge. Else, in hospital, visits will end with V7