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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Photochem Photobiol. 2020 Apr 23;96(3):550–559. doi: 10.1111/php.13253

Figure 1:

Figure 1:

Induction of Anti-tumor Immunity by PDT. PDT of tumors causes immunogenic cell death that is characterized by the release of immune activating DAMPs and is accompanied by induction of acute inflammation that leads to IL-17 dependent neutrophil infiltration into the treated tumor bed and tumor draining lymph node. DAMPs stimulate dendritic cell maturation; mature dendritic cells work in concert with neutrophils to enhanced anti-tumor specific CD8+ T cell activation and increased tumor cell death.