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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Gynecol Oncol. 2020 Mar 23;157(3):716–722. doi: 10.1016/j.ygyno.2020.03.016

Table 2.

Univariable and multivariable odds ratios (ORs) and 95% confidence intervals (CIs) for associations between epidemiological, tumor, and hospital characteristics and GCC, N = 30,426.

Guideline concordant treatment, n (Row %) Univariable OR (95% CI) P Multivariable OR (95% CI)a P
No (n = 17,089) Yes (n = 13,337)
Race/ethnicity 0.46 0.59
 NHW 11,937 (56.4%) 9240 (43.6%) 1.00 1.00
 NHB 3714 (55.8%) 2943 (44.2%) 1.02 (0.97–1.08) 1.01 (0.95–1.07)
 Hispanic 951 (56.3%) 738 (43.7%) 1.00 (0.91–1.11) 1.01 (0.91–1.12)
 AS/PI 487 (53.9%) 416 (46.1%) 1.10 (0.97–1.26) 1.10 (0.96–1.26)
Age <0.0001 <0.0001
 18–44 261 (60.0%) 174 (40.0%) 1.00 1.00
 45–54 1037 (56.9%) 786 (43.1%) 1.14 (0.92–1.41) 1.30 (0.98–1.73)
 55–64 5022 (55.3%) 4065 (44.7%) 1.21 (1.00–1.48) 1.37 (1.04–1.81)
 65–74 6153 (54.5%) 5143 (45.5%) 1.25 (1.03–1.52) 1.40 (1.06–1.84)
 ≥75 4616 (59.3%) 3169 (40.7%) 1.03 (0.85–1.25) 1.19 (0.90–1.57)
Stage <0.0001 <0.0001
 I 80 (47.9%) 87 (52.1%) 1.00 1.00
 IA 3016 (39.0%) 4710 (61.0%) 1.44 (1.06–1.95) 1.53 (1.12–2.08)
 IB 2824 (67.5%) 1359 (32.5%) 0.44 (0.32–0.60) 0.46 (0.33–0.62)
 IC 547 (53.8%) 470 (46.2%) 0.79 (0.57–1.10) 0.82 (0.59–1.14)
 II 1087 (74.1%) 381 (26.0%) 0.32 (0.23–0.45) 0.33 (0.24–0.46)
 IIA 274 (61.6%) 171 (38.4%) 0.57 (0.40–0.82) 0.61 (0.43–0.88)
 IIB 443 (56.2%) 346 (43.9%) 0.72 (0.51–1.00) 0.76 (0.54–1.06)
 III 117 (64.6%) 64 (35.4%) 0.50 (0.33–0.77) 0.53 (0.35–0.82)
 IIIA 1422 (57.0%) 1075 (43.1%) 0.70 (0.51–0.95) 0.73 (0.53–1.00)
 IIIB 409 (67.7%) 195 (32.3%) 0.44 (0.31–0.62) 0.45 (0.31–0.63)
 IIIC 3236 (59.1%) 2244 (41.0%) 0.64 (0.47–0.87) 0.67 (0.49–0.91)
 IV 348 (67.8%) 165 (32.2%) 0.44 (0.31–0.62) 0.47 (0.33–0.67)
 IVA 365 (64.2%) 204 (35.9%) 0.51 (0.36–0.73) 0.54 (0.38–0.76)
 IVB 2921 (61.0%) 1866 (39.0%) 0.59 (0.43–0.80) 0.62 (0.45–0.84)
Histology <0.0001 <0.0001
 Carcinosarcoma 6030 (53.8%) 5177 (46.2%) 1.00 1.00
 Clear cell 1971 (57.6%) 1451 (42.4%) 0.86 (0.79–0.93) 0.78 (0.72–0.84)
 Serous 9088 (57.5%) 6709 (42.5%) 0.86 (0.82–0.90) 0.78 (0.74–0.82)
Charlson comorbidity score 0.72
 0 12,617 (56.0%) 9901 (44.0%) 1.00 -
 1 3639 (56.8%) 2772 (43.2%) 0.97 (0.92–1.03) -
 2 668 (55.8%) 529 (44.2%) 1.01 (0.90–1.13) -
 ≥3 165 (55.0%) 135 (45.0%) 1.04 (0.83–1.31) -
Hospital type 0.04 0.02
 Community cancer program 679 (55.7%) 541 (44.3%) 1.00 1.00
 Comprehensive community cancer program 6329 (57.3%) 4717 (42.7%) 0.94 (0.83–1.05) 0.90 (0.80–1.02)
 Academic/research program 7877 (55.4%) 6353 (44.7%) 1.01 (0.90–1.14) 0.97 (0.86–1.10)
 Integrated network cancer program 2096 (56.2%) 1637 (43.9%) 0.98 (0.86–1.12) 0.93 (0.81–1.06)
 Other/unknown 108 (54.8%) 89 (45.2%) 1.03 (0.76–1.40) 1.30 (0.86–1.96)
Hospital location <0.0001
 Northeast 4244 (57.6%) 3131 (42.5%) 1.00
 South 5976 (55.4%) 4820 (44.7%) 1.09 (1.03–1.16) -
 Midwest 3995 (55.0%) 3273 (45.0%) 1.11 (1.04–1.19) -
 Mountain 657 (62.2%) 399 (37.8%) 0.82 (0.72–0.94) -
 Pacific 2109 (56.5%) 1625 (43.5%) 1.04 (0.97–1.13) -
 Unknown 108 (54.8%) 89 (45.2%) 1.12 (0.84–1.48) -
Urban/rural 0.99
 Metro 14,035 (56.2%) 10,962 (43.9%) 1.00 -
 Urban 2203 (56.1%) 1721 (43.9%) 1.00 (0.94–1.07) -
 Rural 311 (56.9%) 236 (43.1%) 0.97 (0.82–1.15) -
 Unknown 540 (56.4%) 418 (43.6%) 0.99 (0.87–1.13) -
Incomeb 0.20
 ≤$38,000 3357 (56.2%) 2613 (43.8%) 1.00 -
 $38,000-$47,999 3723 (56.2%) 2908 (43.9%) 1.00 (0.94–1.08) -
 $48,000-$62,999 4337 (55.5%) 3484 (44.6%) 1.03 (0.96–1.10) -
 ≥$63,000 5450 (56.5%) 4192 (43.5%) 0.99 (0.93–1.06) -
 Unknown 222 (61.3%) 140 (38.7%) 0.81 (0.65–1.01) -
Education (% without high school diploma)c 0.27
 ≥21% 3268 (57.0%) 2467 (43.0%) 1.00 -
 13%−20.9% 4414 (55.9%) 3483 (44.1%) 1.05 (0.98–1.12) -
 7%−12.9% 5257 (55.9%) 4155 (44.2%) 1.05 (0.98–1.12) -
 <7% 3938 (56.0%) 3095 (44.0%) 1.04 (0.97–1.18) -
 Unknown 212 (60.7%) 137 (39.3%) 0.86 (0.69–1.07) -
Insurance <0.0001 <0.0001
 None 530 (55.6%) 424 (44.4%) 1.00 1.00
 Private 5842 (55.7%) 4655 (44.4%) 1.00 (0.87–1.14) 0.99 (0.86–1.13)
 Medicaid 862 (58.2%) 618 (41.8%) 0.90 (0.76–1.06) 0.93 (0.79–1.10)
 Medicare 9450 (56.1%) 7392 (43.9%) 0.98 (0.86–1.12) 1.04 (0.90–1.21)
 Other government 114 (52.5%) 103 (47.5%) 1.13 (0.84–1.52) 1.11 (0.82–1.51)
 Unknown 291 (66.7%) 145 (33.3%) 0.62 (0.49–0.79) 0.65 (0.51–0.83)
a

Hospital location not included in adjusted model due to collinearity with facility type.

b

Income: quartiles based on equally proportioned income ranges among all U.S. zip codes.

c

Education: quartiles based on proportion of adults in the patient’s zip code who did not graduate from high school.