Table 1:

Demographics of the Fontan Cohort

	Fontan 1 2003–2004	Fontan 2 2009–2011	Fontan 3 2013–2014
N	546	427	362
Males (n, %)	329 (60%)	249 (58%)	221 (61%)
Mean age (yrs; mean±SD)	12 ± 3.4	19 ± 3.4	21 ± 3.5
Transplanted before next study visit (n)	NA	13	1
Death before next study visit (n)	16	10	6
Lost to Follow-up or unwilling to consent (n)	NA	80 (from F1-F2)	58 (from F2-F3)
Anthropometry
Height z-scores (mean±SD)	−0.67 ± 1.27 (N=544)	−0.60 ± 1.34 (N=423)	−0.43 ± 1.14 (N=362)
BMI z-scores (ages ≤20 years; mean±SD)	−0.05 ± 1.13 (N=544)	−0.06 ± 1.26 (N=288)	−0.15 ± 1.27 (N=161)
BMI (ages >20 years; mean±SD)	NA	24.08 ± 4.22 (N=135)	24.38 ± 4.81 (N=201)
Change in Anthropometry
Change in Height z-scores from F1 (mean±SD)	NA	0.04±0.91 (N=421)	0.17±0.85 (N=361)
Change in BMI z-scores from F1 (ages ≤20 years; mean±SD)	NA	0.08±0.92 (N=421)	0.13±0.95 (N=361)
Change in BMI from F2 (ages >20 years; mean±SD)	NA	NA	3.99±3.58 (N=102)
Ventricular Morphology
RV (n, %)	184 (34%)	140 (33%)	112 (31%)
LV (n, %)	265 (48%)	214 (50%)	186 (51%)
Mixed (n, %)	97 (18%)	73 (17%)	64 (18%)
Quality of Life
PedsQL
Total PedsQL Score	NA	74.19±16.15 (N=405)	74.67±16.36 (N=362)
Physical Functioning	NA	74.69±18.24 (N=403)	74.21±19.38 (N=362)
Perceived Physical Appearance	NA	76.93±23.71 (N=401)	79.49±23.96 (N=362)
Emotional functioning	NA	73.67±20.55 (N=403)	73.54±21.37 (N=362)
Social functioning	NA	78.24±20.28 (N=404)	79.64±18.52 (N=362)
School functioning	NA	70.21±19.93 (N=402)	71.21±20.25 (N=362)
Psychosocial health summary	NA	73.98±16.90 (N=404)	74.92±16.80 (N=362)
Health problems and treatment	NA	68.24±19.53 (N=405)	68.74±18.92 (N=362)
Treatment II	NA	89.00±13.32 (N=352)	77.54±33.76 (N=362)
Treatment anxiety	NA	81.06±23.76 (N=403)	82.99±22.50 (N=362)
Cognitive problem	NA	67.23±22.64 (N=402)	68.57±22.65 (N=362)
Communication problem	NA	72.88±25.01 (N=401)	74.26±24.37 (N=362)
Exercise Testing
VO2 Max (mean±SD)	64.55±16.41 (N=403)	NA	58.15±17.12 (N=336)
Change in VO2 Max from F1 (mean±SD)	NA	NA	−7.36±16.83 (N=264)