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. 2020 May 27;117(23):12980–12990. doi: 10.1073/pnas.1917479117

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Fig. 6. — Similar Treg numbers but increased systemic Ova-specific IgE in Ova-patch immunized Langerin-AhR^−/− mice. (A) Following epicutaneous Ova sensitization, LN cells were harvested to characterize CD4⁺CD25⁺foxp3⁺ Treg. Quantitative data for the number of Tregs are shown on the Right. (B) Systemic levels of total and Ova-specific IgE in B6, AhR-loxP, Langerin-AhR^+/−, and Langerin-AhR^−/− mice were measured by ELISA. Ova-specific IgE was significantly increased in the peripheral blood of Langerin-AhR^−/− mice (three independent experiments, n = 5 mice per group). *P < 0.05.