Table 1.

Association between OATP1B3 expression and clinicopathological features of HCC patients

Characteristics		n	OATP1B3 Low	OATP1B3 High	χ2	P
HCC		131	78	53	24.236	< 0.0001
Nontumor liver		89	23	66
Age (year)	≥ 50	56	33	23	0.015	0.902
	< 50	75	45	30
Sex	Male	104	61	43	0.165	0.684
	Female	27	17	10
Tumor size (cm)	≥ 5	88	59	29	6.266	0.012
	< 5	43	19	24
TNM stage	I, II	50	19	31	15.578	< 0.0001
	III, IV	81	59	22
Tumor differentiation	Well	9	0	9	17.716	< 0.0001
	Moderate	101	61	40
	Poor	21	17	4
Serum AFP	≥ 20 ng/mL	89	55	34	0.586	0.444
	< 20 ng/mL	42	23	19
Recurrence	Yes	81	56	25	8.109	0.004
	No	50	22	28
HBsAg	Positive	106	61	45	0.918	0.338
	Negative	25	17	8
Tumor number	Single	87	47	40	3.275	0.07
	Multiple	44	31	13
Liver cirrhosis	Yes	91	53	38	0.209	0.647
	No	40	25	15
Invasion	Yes	58	36	22	0.276	0.599
	No	73	42	31
Tumor capsule	Yes	45	27	18	0.006	0.938
	No	86	51	35

AFP alpha fetoprotein, OATP1B3 organic anion transporting polypeptide 1B3, TNM stage tumor node metastasis stage, HCC hepatocellular carcinoma