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Hydrolysis of human antimicrobial peptides by Pd_dinase. (A) KAMP-14 is sequentially cleaved by Pd_dinase to a 12-mer and 10-mer. (B) Degradation of KAMP-13 to a 11-mer product is formed at a slower rate than KAMP-14 hydrolysis. The 11-mer product is efficiently cleaved further into a 9-mer peptide. (C) 51.2 of hBD2 is cleaved after 60 min incubation. Relative peak area is calculated from triplicate assays and normalized to the time interval with the highest mean peak area
