FIGURE 3.

T1-weighted gadolinium-enhanced axial brain MRI immediately after BBB disruption with MRgFUS that demonstrates contrast extravasation in a discrete and precise grid pattern (enlarged panel) in regions where sonication was performed. Figure is reprinted from Mainprize T, et al (2019). Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study. Scientific Reports, 9(1), 321. https://doi.org/10.1038/s41598-018-36340-0. The figure is licensed under the Creative Commons Attribution 4.0 International License, http://creativecommons.org/licenses/by/4.0/.