Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 10;14:2295–2306. doi: 10.2147/DDDT.S248115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Li et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Up-regulation of miR-27a induced by nimodipine inhibited the apoptosis of brain tissue cells and enhanced the activity of brain tissue cells. (A) Nimodipine up-regulated Bcl2 and down-regulated caspase 3, caspase 9, Bax by up-regulating miR-27a; (B) Nimodipine inhibited apoptosis by up-regulating miR-27a; (C) nimodipine promoted cell activity by up-regulating miR-27a. In the figure, data differences were compared at 96h; (D) miR-27a mimics up-regulated miR-27a; *Indicated P<0.05, **Indicated P<0.01, and ***Indicated P<0.001.

Abbreviations: NC, negative control; OD, optical density; PI, propidium iodide; FITC, fluorescein isothiocyanate isomer; GLO, pmirGLO plasmid.