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Demand curves for remifentanil in combination with JWH-018, 0.00032 mg/kg/infusion remifentanil alone, 0.0032 mg/kg/infusion JWH-018 alone, and vehicle in rhesus monkeys (n=4). Number of infusions is plotted as a function of the fixed-ratio requirement. Symbols indicate the mean, and error bars indicate ± 1 standard error of the mean. The abscissa and ordinate use logarithmic scaling.
