Table 5.

Correlation between VEGF-A rs833061 (-460T>C) and Clinicopathological Characteristics of Breast Cancer (BC) Patients

Parameters	110	CC	CT	TT	X2	Df	P-value
Age Group
Age >40	70	3	30	37	1.1	2	0.57
Age<40	40	2	21	17
Stage status
Early (I and II)	35	2	21	12	4.51	2	0.1
Advanced (III and IV)	75	3	30	42
Grade I vs Grade II
Grade I	10	1	5	4	4.39	2	0.11
Grade II	32	2	6	24
Grade I	10	1	5	4	1.25	2	0.53
Grade III	68	2	40	26
Estrogen receptor status
Positive	62	3	31	28	0.88	2	0.64
Negative	48	2	20	26
Progesterone Receptor status
Positive	72	2	36	34	2.18	2	0.33
Negative	38	3	15	20
Her2/neu status
Positive	45	3	6	36	33.49	2	0.0001
Negative	65	2	45	18
Distant metastasis status		CC	CT	TT
Positive	78	3	45	30	13.88	2	0.001
Negative	32	2	6	24
Herceptin treatment
Herceptin	30	1	8	21	7.26	2	0.026
No Herceptin	80	4	43	33
Tamoxifen treatment
Tamoxifen	67	2	41	24	15.2	2	0.005
No Tamoxifen	43	3	10	30
Mastectomy treatment
Mastectomy	33	3	16	14	2.62	2	0.26
No Mastectomy	77	2	35	40
Lumpectomy Surgery
Lumpectomy	24	3	11	10	4.62	2	0.9
No Lumpectomy	86	2	40	44