Table 4.
BTB14431 |
Emodin |
Control | |||||||
---|---|---|---|---|---|---|---|---|---|
0.3 mg/kg | I vs VI | 1.7 mg/kg | II vs VII | 2.5 mg/kg | III vs VIII | 5 mg/kg | IV vs IX | V vs X | |
sc tumor weight | p = 0.043 | p = 0.720 | p ≤ 0.01 | p = 0.033 | p = 0.661 | ||||
ip tumor weight | p ≤ 0.01 | p = 0.095 | p = 0.01 | p = 0.230 | p = 0.447 | ||||
Total tumor weight | p ≤ 0.01 | p = 0.182 | p ≤ 0.01 | p ≤ 0.01 | p = 0.661 |
Comparison of subcutaneous (sc), intraperitoneal (ia) and overall median tumor weight at T3 after either intravenous (iv) or intraperitoneal (ip) treatment by varying doses of emodin, BTB14431 and electrolyte solution. Parentheses show the 90% confidence interval. P-value was obtained by Mann-Whitney-U-Test comparison of iv vs. ip therapy. Gray background color marks p values > .05.