Table 4.

Relationship between the general psychopathology and mGluR5 receptor binding in SZ patients examined by calculating Spearman's rank correlation coefficient between scores reached in the tests for psychopathological assessment and BP_ND values in the seven observed brain regions

		Left prefrontal gyrus	Right prefrontal gyrus	Left temporal	Right temporal	Caudate	Putamen	Inferior frontal gyrus
Subjects	N	15	15	15	15	15	15	15
PANSS positive	r	−.488	−.494	−.431	−.469	−.057	−.492	−.522
	p	.065	.061	.109	.078	.025	.062	.046
PANSS negative	r	−.473	−.535	−.714*	−.610	−.679*	−.539	−.639
	p	.075	.04	.003*	.016	.005*	.038	.010
PANSS general	r	−.638	−.679*	−.665*	−.596	−.803*	−.612	−.665*
	p	.01	.005*	.007*	.019	.000*	.015	.007*
PANSS total	r	−.632	−.668*	−.734*	−.669*	−.793*	−.621	−.727*
	p	.011	.007*	.002*	.006*	.000*	.013	.002*
SANS: Affective flattening	r	−.612	−.608	−.669*	−.563	−.631	−.500	−.660*
	p	.015	.016	.006*	.029	.012	.058	.007*
SANS: Alogia	r	−.486	−.541	−.690*	−.561	−.708*	−.475	−.618
	p	.066	.037	.004*	.029	.003*	.074	.014
SANS: Avolition‐apathy	r	−.644	−.687*	−.792*	−.714*	−.762*	−.687*	−.773*
	p	.01	.005*	.000*	.003*	.001*	.005*	.001*
SANS: Anhedonia	r	−.208	−.293	−.482	−.315	−.533	−.177	−.278
	p	.457	.289	.069	.252	.041	.529	.315
SANS: Attentional impairment	r	−.343	−.426	−.549	−.384	−.600	−.343	−.413
	p	.210	.114	.034	.158	.018	.210	.126
SANS: Global score	r	−.411	−.503	−.620	−.463	−.715*	−.401	−.498
	p	.128	.056	.014	.082	.003*	.138	.059
HAMD	r	−.369	−.428	−.590	−.455	−.663*	−.430	−.456
	p	.175	.111	.020	.089	.007*	.110	.088
GAF	r	.547	.606	.707*	.596	.799*	.553	.606
	p	.035	.017	.003*	.019	.000*	.033	.017
GF:SOCIAL	r	.493	.582	.691*	.641	.705*	.497	.525
	p	.073	.029	.006*	.013	.005*	.070	.054
GAF:GLOBAL	r	.478	.561	.719*	.660	.711*	.510	.568
	p	.084	.037	.004*	.01	.004*	.062	.034

Note: *Significant correlations after applying Bonferroni correction (p < .0083).

Abbreviations: GAF, Global Functioning Scale; GF: Role, Global Functioning; GF: Social, Global Functioning: Social; HAMD, Hamilton Depression Rating Scale; PANSS, Positive and Negative Syndrome Scale; SANS, Scale for the Assessment of Negative Symptoms.