Table 7.
Relationship between the neurocognitive performance and mGluR5 receptor binding exploratory examined by calculating Spearman's rank correlation coefficient between scores reached in the neurocognitive tests and BPND for the seven observed brain regions in the patient group
| Left prefrontal gyrus | Right prefrontal Gyrus | Left temporal | Right temporal | Caudate | Putamen | Inferior frontal gyrus | ||
|---|---|---|---|---|---|---|---|---|
| Subjects | N | 15 | 15 | 15 | 15 | 15 | 15 | 15 |
| TMT(A) (s) | r | −.408 | −.445 | −.544 | −.423 | −.571 | −.449 | −.486 |
| p | .131 | .096 | .036 | .117 | .026 | .093 | .066 | |
| CT | r | .531 | .550 | .750* | .615 | .665* | .517 | .576 |
| p | .042 | .033 | .001* | .015 | .007* | .049 | .025 | |
| LNS (sum score) | r | −.051 | −.114 | .082 | .028 | −.022 | −.069 | −.035 |
| p | .857 | .685 | .772 | .921 | .939 | .807 | .903 | |
| LNS (longest sequence) | r | −.090 | −.145 | .016 | −.081 | .039 | −.125 | −.065 |
| p | .749 | .607 | .955 | .773 | .891 | .658 | .817 | |
| CBT—forward | r | .164 | .190 | .311 | .216 | .222 | .170 | .221 |
| p | .559 | .497 | .259 | .439 | .426 | .545 | .429 | |
| CBT—backward | r | .283 | .322 | .245 | .191 | .524 | .255 | .330 |
| p | .307 | .242 | .378 | .495 | .045 | .359 | .230 | |
| RVDLT valid recognitions | r | .193 | .209 | .164 | .079 | .363 | .241 | .220 |
| p | .490 | .454 | .560 | .780 | .183 | .386 | .430 | |
| RVDLT—errors | r | −.048 | −.074 | .026 | .084 | −.204 | −.097 | −.015 |
| p | .866 | .794 | .927 | .765 | .466 | .731 | .957 | |
| Z‐composite score | r | .288 | .307 | .433 | .300 | .500 | .321 | .322 |
| p | .298 | .265 | .107 | .277 | .057 | .243 | .242 | |
| TMT(B) (s) | r | −.203 | −.279 | −.392 | −.398 | −.341 | −.385 | .304 |
| p | .487 | .334 | .166 | .158 | .233 | .175 | .291 | |
| TMT(B)–TMT(A) | r | −.161 | −.231 | −.315 | −.343 | −.271 | −.358 | −.264 |
| p | .583 | .427 | .273 | .230 | .349 | .208 | .361 | |
| TMT(B)/TMT(A) | r | .242 | .169 | .103 | .075 | .084 | .055 | .123 |
| p | .404 | .563 | .725 | .799 | .776 | .852 | .674 |
Note: *Significant correlations after Bonferroni correction (p < .0083).
Abbreviations: CBT, Corsi block‐tapping task; CT, Number‐symbol coding task; LNS, Letter–Number Span (LNS); RVDLT, Rey Visual Design Learning Test; TMT(A), Trail‐Making Test (A); TMT(B), Trail‐Making Test (B).