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. 2020 Apr 29;41(10):2567–2582. doi: 10.1002/hbm.24962

Table 2.

Summary of ROIs identified in control athletes that show significant effects on c1 for demographic factors of age, sex or history of concussion (conc.hx.). Standardized effect sizes are reported in terms of BSRs. Significant effects are noted with “*” (FDR = 0.05 threshold). Brain regions are defined based on the BNA

Brain region Center of mass (MNI coordinates) BSR
Age Sex conc.hx.
1 Middle frontal gyrus L (A9/46d) −27 42 30 −1.05 −4.81* 1.10
2 Orbital gyrus L (A14m) −6 54 −9 −0.11 −3.21* 1.48
3 Precentral gyrus R (A4ul) 36 −18 57 3.56* −1.22 0.09
4 Precentral gyrus R (A4t) 15 −21 72 3.95* 0.14 1.39
5 Paracentral lobule R (A4ll) 6 −21 60 3.79* −2.01 0.16
6 Fusiform gyrus R (A20rv) 33 −15 −30 −0.54 −4.77* 1.24
7 Postcentral gyrus L (A1/2/3tru) −21 −33 69 3.65* −0.63 0.53
8 Medioventral occipital cortex L (cLinG) −12 −81 −12 0.80 −3.32* 0.23
9 Lateral occipital cortex L (iOccG) −30 −87 −12 −0.24 −3.34* 1.89
10 Basal ganglia L (vmPu) −24 6 −3 1.04 −3.48* 1.75
11 Basal ganglia R (dlPu) 30 −3 3 0.71 −3.59* 0.41

Note: A9/46d = dorsal area 9/46, A14m = medial area 14, A4ul = area 4 (upper limb region), A4t = area 4 (trunk region), A4ll = area 4 (lower limb region), A20rv = rostroventral area 4, A1/2/3tru = area 1/2/3 (trunk region).

Abbreviations: BNA, Brainnetome Atlas; BSR, bootstrap ratio; cLinG, caudal lingual gyrus, dlPu, dorsolateral putamen; FDR, false discovery rate; iOccG, inferior occipital gyrus; vmPu, ventromedial putamen.