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. 2020 Apr 29;41(10):2567–2582. doi: 10.1002/hbm.24962

Table 3.

Summary of ROIs identified in concussed athletes that show significant longitudinal change in c1 relative to ACU, as displayed in Figure 4. Standardized effect sizes are reported in terms of BSRs. Significant effects are noted with “*” (FDR = 0.05 threshold). Brain regions are defined based on the BNA

Brain region Center of mass BSR
(MNI coordinates) SUB RTS 1MO 1YR
1 Superior frontal gyrus L (A10m) −9 57 15 0.97 0.85 3.10* 0.06
2 Inferior frontal gyrus L (A45r) −48 36 −3 −0.16 0.64 3.15* 0.70
3 Middle temporal gyrus R (ASTS) 57 −15 −9 1.69 3.33* 1.90 1.50
4 Fusiform gyrus L (A37mv) −30 −63 −15 −0.08 3.52* 1.48 1.28
5 Fusiform gyrus R (A37mv) 30 −60 −15 0.62 4.06* 1.54 1.16
6 Fusiform gyrus R (A37lv) 42 −51 −18 1.14 2.60* 1.72 1.55
7 Posterior superior temporal sulcus L (rpSTS) −54 −39 3 0.23 2.81* 2.72 1.25
8 Medioventral occipital cortex L (rLingG) −18 −60 −6 0.39 5.18* 3.70* 0.78
9 Medioventral occipital cortex L (vmPOS) −12 −69 12 0.72 3.32* 2.78 0.74
10 Medioventral occipital cortex R (vmPOS) 15 −63 12 0.51 3.07* 2.22 1.05
11 Lateral occipital cortex L (mOccG) −30 −90 12 1.42 3.29* 1.34 2.19
12 Lateral occipital cortex R (mOccG) 36 −87 12 0.54 3.56* 1.65 1.76
13 Lateral occipital cortex L (V5/MT+) −45 −75 3 1.44 3.07* 1.97 1.36
14 Lateral occipital cortex R (V5/MT+) 48 −69 0 2.27 3.57* 2.73 2.59
15 Lateral occipital cortex L (iOccG) −30 −87 −12 1.11 2.83* 0.73 1.23
16 Lateral occipital cortex R (msOccG) 15 −84 36 0.94 2.94* 0.32 1.44
17 Thalamus L (cTtha) −12 −21 12 1.89 3.07* 1.94 1.27

Note: A10m = medial area 10, A45r = rostral area 45, ASTS = anterior temporal sulcus, A37mv = medioventral area 37, A37lv = lateroventral area 37, V5/MT+ = area V5/MT+.

Abbreviations: BNA, Brainnetome Atlas; BSR, bootstrap ratio; cTtha, caudal temporal thalamus; iOccG, inferior occipital gyrus; mOccG, middle occipital gyrus; msOccG, medial superior occipital gyrus; rLingG, rostral lingual gyrus, rpSTS, rostroparietal superior temporal sulcus; vmPOS, ventromedial parietooccipital sulcus.