Table 3.

Frequency Comparison of Functional Deletion in HBV Pre-S Region Between the Two Groups

Functional Domain	HIV/HBV Co-Infection	HBV Mono-Infection	P-value
Transactivator domain	31.3% (4.1–94.7%)	16.1% (2.9–48.7%)	0.060
Hepatocyte binding site	13.7% (4.0–96.4%)	5.1% (1.9–22%)	0.180
S-promoter	28.6% (4.1–94.6%)	6.0% (1.9–40.1%)	0.020
Heat shock protein 70 binding site	26.8% (4.1–94.6%)	5.8% (2.0–26.9%)	0.022
Cytosolic anchorage determinant	18.4% (3.9–94.7%)	5.9% (2.1–32.6%)	0.083
CCAAT binding site	18.45% (4.1–94.7%)	11.9% (2.5–49.7%)	0.413
Nucleocapsid binding site	15.8% (2.8–91.9%)	5.9% (2.0–46.7%)	0.233
pHSA binding site	15.8% (3.7–70.8%)	9.1% (2.0–29.7%)	0.281
Viral secretion site	25% (3.3–89.4%)	6% (1.9–29.4%)	0.205

Notes: Data were expressed by median (interquartile range). Bold values indicate P<0.05.

Abbreviation: pHSA, polymerized human serum albumin.