. 2020 Jun 9;12:137–150. doi: 10.2147/JEP.S248677

Table 2.

Effect of 80% Methanol Extract of the Leaves of Clutia abyssinica on Body Weight, Change in Body Weight and Absolute and Relative Liver Weight of Mice Administered with CCl4

Group	Body Weight (g)		Change in Body Weight	Liver Weight (g)	Relative Liver Weight (%)
Group	Initial	Final	Change in Body Weight	Liver Weight (g)	Relative Liver Weight (%)
2%TW80	32.50 ± 1.09	34.62 ± 0.95	2.12 ± 0.52	2.40 ± 0.07	6.94 ± 0.14
CCl4	32.50 ± 0.89	29.34 ± 0.56^a**	−3.16 ± 0.66^a***	3.56 ± 0.21^a**	12.16 ± 0.76^a***
Silymarin + CCl4	32.00 ± 1.03	34.00 ± 0.89^b**	2.00 ± 0.37^b***	2.62 ± 0.19^b*	7.70 ± 0.52^b***
Me100 + CCl4	31.67 ± 0.92	29.19 ± 0.41^a^,c^,d^,e*	−2.48 ± 0.59^a*^,c^,d^,e**	3.28 ± 0.30	11.24 ± 1.02^a*^,c^,e**
Me200 + CCl4	32.50 ± 1.34	34.48 ± 1.31^b**	1.98 ± 0.46^b***	2.86 ± 0.20	8.35 ± 0.67^b**
Me400 + CCl4	32.83 ± 1.02	34.87 ± 0.78^b***	2.04 ± 1.21^b***	2.52 ± 0.23^b*	7.25 ± 0.69^b***

Notes: Each value represents mean ± S.E.M; n=6; ^aAgainst 2%TW80; ^bAgainst CCl4; ^cAgainst standard (silymarin); ^dAgainst Me200 + CCl4; ^eAgainst Me400 + CCl4; *p < 0.05, **p < 0.01, ***p < 0.001.

Abreviations: Me100, 80% methanol extract 100 mg/kg; Me200, 80% methanol extract 200 mg/kg; Me400, 80% methanol extract 400 mg/kg; silymarin, silymarin 100 mg/kg; CCl₄, carbon tetrachloride 2mL/kg; 2%TW80, 2% Tween 80 in water.