. 2020 Apr 21;24(11):6448–6458. doi: 10.1111/jcmm.15293

TABLE 1.

Cardiac mechanical function of isolated rat hearts (mean ± SEM)

Parameter	Aerobic control	I/R	P
HR (bpm) ^a	305.3 ± 6.5	70.7 ± 36.0*	.0002
CF (mL/min) ^b	12.6 ± 1.4	3.2 ± 1.1*	.0024
dP/dt_max (mm Hg/s) ^a	1543 ± 117	1300 ± 51	.0657
dP/dt_min (mm Hg/s) ^a	−1451 ± 113	−1126 ± 78*	.0311
PED (mm Hg) ^a	9.9 ± 0.3	8.7 ± 0.4*	.0266
LVDP (mm Hg) ^a	57.2 ± 2.1	40.4 ± 4.1*	.0032
RPP (mm Hg × min⁻¹ × 10³) ^a	17.4 ± 1.0	10.0 ± 1.0*	<.0001
Recovery (%) ^c	105.5 ± 10.2	74.5 ± 5.3*	.0040

Abbreviations: CF, coronary flow; dP/dt_max, baseline left ventricular maximal contractility; dP/dt_min, baseline left ventricular maximal relaxation; HR, heart rate; I/R, ischaemia/reperfusion; LVDP, left ventricular developed pressure, PED, left ventricular end‐diastolic pressure; n = 4‐14 *P < .05 vs Aerobic control; RPP, rate pressure product.

^{^a}

After I/R (77 min of the experiment).

^{^b}

After ischaemia (first minute of reperfusion).

^{^c}

The difference between RPP in 25 and 77 min of the experiment.