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. 2020 Apr 28;24(11):5984–5997. doi: 10.1111/jcmm.15001

Table 2.

Demographical and clinical features of coronary heart disease (CHD) patients and high‐risk controls in validation set‐1 and validation set‐2

  Validation set‐1 Validation set‐2
High‐risk control CHD P value High‐risk control CHD P value
INDV (n = 48) INDV (n = 48) INDV (n = 60) INDV (n = 95)
Age (y) 53.92 ± 9.02 60.92 ± 12.56 .15 165.53 ± 6.48 168.05 ± 44.83 .27
Female 31 21 .18 65.02 ± 7.19 68.05 ± 19.76 .24
Male 17 27 .65 23.71 ± 1.97 24.07 ± 2.47 .33
Clinical features
Height (cm) 165.69 ± 6.68 167.87 ± 34.69 .15 165.53 ± 6.48 168.05 ± 44.83 .27
Body weight (kg) 66.11 ± 8.19 68.50 ± 16.20 .18 65.02 ± 7.19 68.05 ± 19.76 .24
Body mass index 23.05 ± 2.25 24.27 ± 2.33 .65 23.71 ± 1.97 24.07 ± 2.47 .33
Blood parameter
TCH (mmol/L) 4.71 ± 1.46 4.95 ± 1.72 .36 4.81 ± 1.44 4.78 ± 1.46 .89
TG (mmol/L) 1.61 ± 1.17 2.04 ± 1.56 .15 1.583 ± 1.19 1.64 ± 0.99 .76
HDL (mmol/L) 1.31 ± 0.49 1.34 ± 0.49 .66 1.34 ± 0.53 1.33 ± 0.71 .91
LDL (mmol/L) 3.04 ± 1.15 2.96 ± 1.19 .77 2.94 ± 1.14 3.09 ± 1.11 .39
Hcy (μmol/L) 8.94 ± 5.02 10.75 ± 6.52 .16 9.36 ± 5.29 10.75 ± 6.16 .18
UA (μmol/L) 295.71 ± 134.57 340.88 ± 144.36 .14 290.73 ± 148.27 343.33 ± 153.03 .03
Urea (mmol/L) 5.32 ± 1.24 5.52 ± 1.52 .5 5.23 ± 1.22 5.58 ± 1.69 .19
Creatinine (μmol/L) 65.65 ± 13.64 62.10 ± 14.62 .26 62.89 ± 13.12 66.39 ± 17.98 .21
Apolipoprotein A (g/L) 1.34 ± 0.22 1.45 ± 0.19 .02 1.34 ± 0.25 1.27 ± 0.16 .09
Apolipoprotein B (g/L) 0.86 ± 0.24 0.90 ± 0.29 .47 0.89 ± 0.29 5.71 ± 41.93 .32
Lipoprotein(a) (mg/L) 146.90 ± 130.43 197.79 ± 216.11 .24 139.61 ± 127.29 198.89 ± 215.23 .06
White blood cell (109/L) 6.60 ± 1.73 6.76 ± 1.51 .55 6.56 ± 1.77 6.67 ± 2.12 .72
Lymphocyte (%) 28.99 ± 7.59 27.32 ± 9.38 .35 29.45 ± 8.04 32.52 ± 27.05 .32
Neutrophil granulocyte (%) 61.72 ± 8.88 64.12 ± 11.11 .26 61.41 ± 9.17 59.92 ± 10.11 .36
Red blood cell (1012/L) 4.62 ± 0.62 4.76 ± 0.69 .36 4.58 ± 0.61 4.68 ± 0.51 .34
Hemoglobin (g/L) 167.78 ± 144.88 151.54 ± 15.87 .45 161.79 ± 130.42 146.23 ± 14.94 .38
Hematocrit (%) 41.62 ± 5.35 43.78 ± 4.074 .04 48.81 ± 57.99 42.36 ± 3.98 .41
Platelet (109/L) 241.98 ± 68.48 216.671 ± 50.41 .08 237.67 ± 66.56 220.59 ± 44.74 .11
Other disease
Diabetes mellitus, n (%) 1 (2.08) 7 (14.58)   1 (1.67) 14 (14.74)  
Hypertension, n (%) 12 (25.00) 18 (37.50)   15 (25.00) 43 (45.26)  
Cerebral vascular event, n (%) 0 (0) 1 (2.08)   0 (0) 1 (1.05)  
Smoking status, n(%) Angiocardiography results 7 (14.58) 13 (27.08)   6 (10.00) 27 (28.42)  
LM 1 (slight) 4   1 7  
LAD 14 (slight) 44   22 (slight) 84  
LCX 1 (slight) 32   5 64  
D 0 5   0 11  
OM 0 2   0 4  
RCA 1 (slight) 42   5 (slight) 76  
PD 0 0   0 5  
PL 0 0   0 3  

Abbreviations: D, diagonal branch; Hcy, homocysteine; HDL, high‐density lipoprotein; INDV, individual; LAD, left anterior descending; LCX, left circumflex branch; LDL, low‐density lipoprotein; LM, left main coronary artery; OM, obtuse marginal branch; PD, posterior descending branch; PL, posterior branch of left ventricle; RCA, right coronary artery; TCH, total cholesterol; TG, triglycerides; UA, uric acid.