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. 2020 May;142:24–38. doi: 10.1016/j.yjmcc.2020.04.001

Table 1.

Experimental AP biomarkers.

BCL (ms)
400
500
700
1000
1500
2000
3000
5000
Min Max Min Max Min Max Min Max Min Max Min Max Min Max Min Max
dV/dtMax (V/s) 242 576 176 674 176 644 154 688 195 605 195 625 195 625 151 625
APD90 (ms) 167 288 173 338 175 389 187 438 177 445 178 415 179 470 180 497
APD75 (ms) 146 253 150 298 151 346 166 384 155 394 157 371 157 421 159 453
APD50 (ms) 114 199 118 246 121 292 124 349 122 339 127 292 125 365 129 392
APD25 (ms) 32 137 39 148 45 167 31 185 34 209 20 147 19 218 25 226
APD10 (ms) 2 65 1.4 63 1 82 1 107 1 75 1 23 1 86 1 91
APA (mV) 101 115 101 115 91 115 93 116 93 122 92 115 94 123 89 115
TOP (mV) −88 −80 −89 −75 −90 −76 −91 −79 −92 −77 −87 −76 −93 −77 −88 −73
EOP (mV) −91 −85 −89 −79 −90 −75 −94 −81 −93 −77 −89 −77 −93 −77 −88 −72

Minimum and maximum experimental values for the 9 AP biomarkers recorded in human cardiac Purkinje cells at multiple BCL: 400 ms (n = 7), 500 ms (n = 7), 700 ms (n = 9), 1000 (n = 17), 1500 ms (n = 9), 2000 ms (n = 7), 3000 (n = 8), 5000 ms (n = 8).

BCL: Basic cycle length; dV/dtMAX: maximum upstroke velocity; APDx: AP duration at X% of repolarisation; APA: action potential amplitude; TOP: membrane potential before depolarisation; EOP: membrane potential at the end of repolarisation.