Supplemental Table 3.
Clinical management and outcomes
| Variable | Patients (n=13) |
|---|---|
| ICU management | |
| Invasive mechanical ventilation | 8 (62) |
| Duration, d | 8 (2–19) |
| Extubateda | 6/8 (75) |
| Prone positioning utilized | 4/8 (50) |
| Extracorporeal membrane oxygenation | 0 (0) |
| Vasopressors | 7 (54) |
| Renal replacement therapy | 1 (8) |
| Antiviral agent | |
| Hydroxychloroquine | 11 (85) |
| Remdesivir | 3 (23) |
| Antibiotics for community-acquired pneumonia | 12 (92) |
| Anticoagulation, prophylactic or therapeutic | 13 (100) |
| Immunomodulatory agent | 9 (69) |
| Corticosteroid (for maternal indication) | 7 (54) |
| Interleukin-1 inhibitor | 2 (15) |
| Interleukin-6 inhibitor | 5 (38) |
| Convalescent plasma | 2 (15) |
| Maternal outcomes | |
| Length of stay, d | |
| In hospital | 13 (9–23) |
| In ICU | 8 (4–15) |
| Delivery during hospitalization | 7/13 (54) |
| Cesarean delivery for acute respiratory decompensation | 5/7 (71) |
| Cesarean delivery for obstetrical indication | 1/7 (14) |
| Vaginal delivery | 1/7 (14) |
| Died in hospital | 2 (15) |
| Discharged from hospital | 11 (85) |
| To home | 10 (77) |
| To long-term care facility | 1 (8) |
| Remained hospitalized at study completion | 0 (0) |
| Neonatal outcomes | |
| Gestational age at delivery, wk | 36.9±2.0 |
| Birthweight, g | 2994±569 |
| Apgar scores | |
| 1 min≤7 | 3/8 (38) |
| 5 min≤7 | 0/8 (0) |
| Positive PCR result for SARS-CoV-2 on first day of lifeb | 0/7 (0) |
| Received antenatal corticosteroids | 5 (50) |
| Gestational age at administration | 29.1±4.2 |
Data are presented as n (%), mean±standard deviation, and median (interquartile range). Denominator is number of patients diagnosed as having COVID-19 at less than 37 weeks’ gestation.
COVID-19, coronavirus disease 2019; ICU, intensive care unit; PCR, polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Blitz. Maternal mortality among intensive care unit admissions for coronavirus disease 2019. Am J Obstet Gynecol 2020.
a
One patient was extubated but remained ventilator dependent with a tracheostomy
b
Results not available for 1 newborn.